First observe that the second statement follows from the first since any simple closed curve can be written as the union of two arcs intersecting at exactly their two endpoints.
Next, observe that under the given hypotheses we have \(C\subsetneq S^2\text{.}\) Indeed, the space \(C-\{P,Q\}\) is easily seen to be disconnected, whereas the doubly punctured sphere is connected.
Now assume by contradiction that \(S^2-C\) is connected. We will show that this implies \(\pi_1(S^2-\{P,Q\}, R)\) is trivial for any \(R\ne P,Q\text{:}\) an absurdity since \(S^2-\{P,Q\}\) is homeomorphic to the punctured plane, which has fundamental group isomorphic to \(\Z\text{.}\)
Let \(U=S^2-A_1\) and \(V=S^2-A_2\text{,}\) in which case we have
\begin{align*}
U\cup V \amp = S^2-(A_1\cap A_2)=S^2-\{P,Q\}\\
U\cap V \amp = S^2-(A_1\cup A_2)=S^2-C\ne \emptyset\text{.}
\end{align*}
Since
\(U\cap V=S^2-C\) is connected (by assumption), and since
\(S^2\) is locally path connected,
\(U\cap V\) is path connected. This means we are in the position to use the
weak Seifert-van Kampen theorem. Let
\(i\colon U\subseteq S^2-\{P,Q\}\) and
\(j\colon V\subseteq S^2-\{P,Q\}\) be the inclusion maps, and pick any
\(R\in U\cap V=S^2-C\text{.}\) We will show that
\begin{align*}
i_*\colon \pi_1(U, R) \amp \rightarrow \pi_1(S^2-\{P,Q\},R)\\
j_*\colon \pi_1(V, R) \amp \rightarrow \pi_1(S^2-\{P,Q\},R)
\end{align*}
are both trivial maps, which would imply \(S^2-\{P,Q\}\) has trivial fundamental group: a contradiction.
It will suffice by symmetry to show
\(i_*\) is trivial. Recall that
\(i_*([f])=[i\circ f]\) for any
\([f]\in \pi_1(U,R)=\pi_1(S^2-A_1,R)\text{.}\) Since
\(f\colon I\rightarrow U\) is a loop, letting
\(q\colon I\rightarrow S^1\) be the standard quotient map, there is a map
\(h\colon S^1\rightarrow U\) making the diagram below commutative.

Factorization of \(f\) through \(S^1\)
Consider the map
\(i\circ h\colon S^1\rightarrow S^2-\{P,Q\}\text{.}\) Its image
\(i\circ h(S^1)=h(S^1)\) lies in
\(S^2-A_1\text{.}\) Since
\(A_1\) is a connected set containing
\(P\) and
\(Q\text{,}\) we see that these two points lie in the same component of
\(S^2-i\circ h(S^1)\text{.}\) We conclude from
Lemma 2.10.7 that
\(i\circ h\) is nullhomotopic. It now follows from
Corollary 2.7.4 that the map
\((i\circ h)_*\) is trivial. But then we have
\begin{align*}
i_*([f]) \amp = [i\circ f]\\
\amp = [i\circ h\circ q] \amp (f=h\circ q)\\
\amp = (i\circ h)_*([q])\\
\amp = e \text{,}
\end{align*}
since \((i\circ h)_*\) is the trivial map. This proves that \(i_*\) is trivial, as desired.